Epithelial esenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res 2013; 19: 27990. 27. Fernando RI, Hamilton DH, Dominguez C, David JM, McCampbell KK, Palena C. IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib. Oncotarget 2016; 7: 420312044. 28. Akalay I, Janji B, Hasmim M, Noman MZ, Thiery JP, Mami-Chouaib F et al. EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis by way of autophagy induction. Autophagy 2013; 9: 1104106.Cell Death and DiseaseErlotinib enhances immune lysis of tumor cells C Dominguez et al56. Heery CR, Singh BH, Rauckhorst M, Marte JL, Donahue RN, Grenga I et al. Phase I trial of a yeast-based therapeutic cancer vaccine (GI-6301) targeting the transcription issue brachyury. Cancer Immunol Res 2015; three: 1248256. 57. http://www.clinicaltrials.gov/. Security and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM) 2014. Readily available from: http://www.clinicaltrials.gov/ct2/show/ NCT02179515. 58. Madan RA, Gulley JL, Fojo T, Dahut WL. Therapeutic cancer vaccines in prostate cancer: the paradox of enhanced survival without alterations in time for you to progression.Boc-NH-PEG11-NH2 Purity Oncologist 2010; 15: 96975. 59. Tucker JA, Jochems C, Boyerinas B, Fallon J, Greiner JW, Palena C et al. Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription aspect involved in epithelial to mesenchymal transition and metastasis. Cancer Immunol Immunother 2014; 63: 1307317. 60. Jochems C, Tucker JA, Vergati M, Boyerinas B, Gulley JL, Schlom J et al. Identification and characterization of agonist epitopes on the MUC1-C oncoprotein. Cancer Immunol Immunother 2014; 63: 16174. 61. Hamilton DH, Fernando RI, Schlom J, Palena C. Aberrant expression on the embryonic transcription element brachyury in human tumors detected with a novel rabbit monoclonal antibody. Oncotarget 2015; six: 4853862. 62. Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev 2006; 20: 1496510.Cell Death and Disease is definitely an open-access journal published by Nature Publishing Group. This work is licensed below a Inventive Commons Attribution four.0 International License. The images or other third party material in this post are included within the article’s Creative Commons license, unless indicated otherwise inside the credit line; if the material will not be integrated below the Inventive Commons license, customers will need to acquire permission in the license holder to reproduce the material.942518-20-9 supplier To view a copy of this license, visit http://creativecommons.PMID:34235739 org/licenses/by/4.0/ r The Author(s)Supplementary Info accompanies this paper on Cell Death and Illness web-site (http://www.nature.com/cddis)Cell Death and Illness
Cellular and Molecular Bioengineering, Vol. ten, No. 5, October 2017 (2017) pp. 34155 DOI: ten.1007/s12195-017-0505-Adjuvant-Loaded Spiky Gold Nanoparticles for Activation of Innate Immune CellsJUTAEK NAM,1,two SEJIN SON,1,two,three and JAMES J. MOON1,two,1 Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA; 2Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; 3De.
